Biological Services
Biological Division
CERBIOS’ interest in supplying services is to support its partners and customers in the field of CERBIOS’ competences with the goal to supply them with material for clinical trials and/or commercial production.
As a leading company in pharmaceutical probiotics, having all analytical tools in house, CERBIOS has a deep know-how and expertise in fermentation processes for both, procaryotic and eucaryotic cells. Choice of suitable media components and correct handling of master and working cell banks are key factors for a reproducible and safe production. From a commercial point of view, one of the most critical key factors is time to market. CERBIOS has a proven track record for the implementation of a completely new building harbouring a new fermentation plant in 18 months from signature of contract to commercial production.
In the field of recombinant proteins produced by CHO & microorganisms, CERBIOS is able to offer ”full service” including development, starting with cloning of recombinant proteins and ending up with process optimization and validation, analytics development and validation, as well as cGMP-manufacturing of biopharmaceuticals compliant to EMEA and FDA guidelines. The cultivation media used by CERBIOS for its CHO platform are “state of the art”, serum-free, protein-free, antibiotic-free and free of any component of animal origin. These completely synthetic media may be adapted, case by case, to the cell line and the protein to be expressed. This allows for optimization of key parameters including productivity and yield. Based on this technology CERBIOS has already successfully developed recombinant proteins, such as rUK and G-CSF.
Our services include:
- CHO or microorganism development of therapeutic proteins for pre-clinical and clinical trials
- Upstream & downstream process development
- cGMP manufacturing, analytics and release of biological products
- Cell banking and repository
Of particular interest are projects taking advantage of the synergies between the Biological and the Chemical Division of CERBIOS, giving the potential for development and manufacturing of conjugates or small molecules, also using bioconversion catalytical step technology.
You may find more details about our services if you click on the service and contract manufacturing inquiry form.
